Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Dopamine D2 receptor signaling: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Smartphone-Detected Motor Variability Correction | 0.563 | neurodegeneration | Digital biomarkers and AI-driven early d |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-01 | 7 hypotheses Top: 0.605
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Atremorine in Parkinson's disease: From dopaminergic neuroprotection to pharmaco [PMID:34106485] | Cacabelos R, Carrera I, Martínez O, Alej | Med Res Rev | 2021 | 1 |
| Age-dependent nigral dopaminergic neurodegeneration and α-synuclein accumulation [PMID:31120439] | Luo Z, Ahlers-Dannen KE, Spicer MM, Yang | JCI Insight | 2019 | 1 |
| Targeting alpha synuclein and amyloid beta by a multifunctional, brain-penetrant [PMID:31873106] | Yedlapudi D, Xu L, Luo D, Marsh GB, Todi | Sci Rep | 2019 | 1 |
| A systematic review and integrative approach to decode the common molecular link [PMID:28927418] | Guin D, Mishra MK, Talwar P, Rawat C, Ku | BMC Med Genomics | 2017 | 1 |
| The role of genetic factors in the occurrence of levodopa-induced motor complica [PMID:40632937] | ["Radojevi\u0107 B", "Milovanovi\u0107 A | Neurological research | 2026 | 0 |
| Reliability and Discriminant Ability of an Instrumented Timed Up and Go Test in [PMID:41921127] | ["Giardini M", "Arcolin I", "Arcobelli V | JMIR rehabilitation and assist | 2026 | 0 |
| Evaluating the Utility of Wearable Sensors for the Early Diagnosis of Parkinson [PMID:40690754] | ["Li H", "Zecca M", "Huang J"] | Journal of medical Internet re | 2025 | 0 |
| Effectiveness of instruments for assessing physical activity in adolescents: a s [PMID:41093309] | ["Kuanysh Z", "Vlassova A", "Seidakhmeto | Physical activity and nutritio | 2025 | 0 |
| Smartphone-based prediction of dopaminergic deficit in prodromal and manifest Pa [PMID:41326766] | ["Gunter K", "Groenewald K", "Aubourg T" | NPJ digital medicine | 2025 | 0 |
| Wearable Sensor-Based Assessments for Remotely Screening Early-Stage Parkinson's [PMID:39275547] | ["Johnson S", "Kantartjis M", "Severson | Sensors (Basel, Switzerland) | 2024 | 0 |
| Enhancement of Haloperidol-Induced Catalepsy by GPR143, an L-Dopa Receptor, in S [PMID:38286627] | ["Arai M", "Suzuki E", "Kitamura S", "Ot | The Journal of neuroscience : | 2024 | 0 |
| Digital biomarkers in Parkinson's disease. [PMID:39181623] | ["Bougea A"] | Advances in clinical chemistry | 2024 | 0 |
| Recent Advances in representative small-molecule DRD2 inhibitors: Synthetic Rout [PMID:39098130] | ["Zhang Y", "Yu J", "Wen W"] | European journal of medicinal | 2024 | 0 |
| Wearable sensor-based gait analysis to discriminate early Parkinson's disease fr [PMID:36725698] | ["Lin S", "Gao C", "Li H", "Huang P", "L | Journal of neurology | 2023 | 0 |
| Associations between variants in levodopa metabolic pathway genes and levodopa-i [PMID:36813078] | ["Yan J", "Ge Y", "Wang P", "Li W", "Jin | Neuroscience letters | 2023 | 0 |
| Remote smartphone monitoring of Parkinson's disease and individual response to t [PMID:34373643] | ["Omberg L", "Chaibub Neto E", "Perumal | Nature biotechnology | 2022 | 0 |
| Wearable sensor device-based detection of decreased heart rate variability in Pa [PMID:35835890] | ["Suzuki M", "Nakamura T", "Hirayama M", | Journal of neural transmission | 2022 | 0 |
| In Parkinson's patient-derived dopamine neurons, the triplication of α-synuclein [PMID:34099060] | ["Lin M", "Mackie P", "Shaerzadeh F", "G | Acta neuropathologica communic | 2021 | 0 |
| Pharmacogenetics-Guided Advances in Antipsychotic Treatment. [PMID:34129738] | ["Islam F", "Men X", "Yoshida K", "Zai C | Clinical pharmacology and ther | 2021 | 0 |
| Patient, study thyself. [PMID:30470218] | ["Wicks P"] | BMC medicine | 2018 | 0 |